Kybella
What is Kybella
2002
KYBELLA injection is injected into subcutaneous fat tissue in the submental area using an area-adjusted dose of 2 mg/cm2 A single treatment consists of up to a maximum of 50 injections, 0.2 mL each (up to a total of 10 mL), spaced 1 cm apart. Up to 6 single treatments may be administered at intervals no less than 1 month apart
KYBELLA should be administered by a healthcare professional.
Screen patients for other potential causes of submental convexity/fullness (e.g., thyromegaly and cervical lymphadenopathy). Give careful consideration to the use of KYBELLA in patients with excessive skin laxity, prominent platysmal bands or other conditions for which reduction of submental fat may result in an aesthetically undesirable outcome.
The safe and effective use of KYBELLA depends on the use of the correct number and locations
for injections, proper needle placement, and administration techniques.
Healthcare professionals administering KYBELLA must understand the relevant submental anatomy and associated neuromuscular
structures in the area involved and any alterations to the anatomy due to prior surgical or aesthetic procedures [see Warnings and Precautions
Injection: 10 mg/mL.
KYBELLA (deoxycholic acid) injection is a clear, colorless, sterile solution supplied in 2 mL vials intended for single patient use. Each milliliter of the solution contains 10 mg of deoxycholic acid.
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Injection Technique
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The safe and effective use of KYBELLA depends on the use of the correct number and locations
for injections, proper needle placement, and administration techniques.
Healthcare professionals administering KYBELLA must understand the relevant submental
anatomy and associated neuromuscular structures in the area involved and any alterations to the anatomy due to prior surgical or aesthetic procedures [see Warnings and Precautions].
Avoid the Marginal Mandibular Nerve Area
Prior to each treatment session, palpate the submental area to ensure sufficient submental fat
and to identify subcutaneous fat between the dermis and platysma (pre-platysmal fat) within the
target treatment area .The number of injections and the number of treatments should
be tailored to the individual patient’s submental fat distribution and treatment goals.
Injecting into the treatment area
Use of ice/cold packs, topical and/or injectable local anesthesia (e.g., lidocaine) may enhance
patient comfort. Outline the planned treatment area with a surgical pen and apply a 1 cm injection grid to mark the injection sites .
Treatment Area and Injection Pattern
1) Using a large bore needle, draw 1 mL of KYBELLA into a sterile 1 mL syringe and expel any air bubbles in the syringe barrel.
2) Injections that are too superficial (into the dermis) may result in skin ulceration and necrosis.
3) Avoid injecting into the post-platy small fat by injecting KYBELLA into fat tissue at the
depth of approximately mid-way into the subcutaneous fat layer
4) Avoid injecting into other tissues such as the muscle, salivary glands, lymph nodes; and
artery or vein.
5) Avoid injecting into other tissues such as the muscle, salivary glands, lymph nodes; and
artery or vein.
